What is Tizanidine?

Tizanidine is the generic name for a well know brand name medication, Zanaflex. It is a short-acting muscle relaxer that works by blocking nerve impulses (pain sensations) that are sent to your brain. Tizanidine is used to treat spasticity by temporarily relaxing muscle tone.

Tizanidine is a short-acting medication that should be taken only for daily activities that require relief from muscle spasticity.

Important Information about Tizanidine

Too much Trizanidine can damage your liver. Do not take more than three doses (36 mg) of tizanidine in a 24-hour period.

Trizanidine interacts with many different medications. It is important to tell your doctor if you are taking any Cold or allergy medicine, narcotic pain medicine, sleeping pills, other muscle relaxers, and medicine for seizures, depression or anxiety. These medications can add to sleepiness caused by tizanidine.

Tizanidine Side Effects

Along with the desired effects of Tizanidine there are many side effects associated with this medication. Most commonly patients will experience side effects to Tizandine that do not require medical attention, including;

  • Anxiety
  • back pain
  • constipation
  • depression
  • diarrhea
  • difficulty in speaking
  • dizziness or lightheadedness, especially when getting up from a lying or sitting position
  • drowsiness
  • dry mouth
  • heartburn
  • increased sweating
  • increased muscle spasms or tone
  • muscle weakness
  • pain or burning in throat
  • runny nose
  • skin rash
  • sleepiness
  • stomach pain
  • uncontrolled movements of the body

Other common side effects to Tizanidine will require medical attention, these include;

  • Chest pain or discomfort
  • fever
  • loss of appetite
  • lower back or side pain
  • nausea and/or vomiting
  • nervousness
  • pain or burning while urinating
  • painful or difficult urination
  • sores on the skin
  • tingling, burning, or prickling sensations
  • unusual tiredness
  • yellow eyes or skin

Tizanidine Uses

Tizanidine is used to treat spasticity by temporarily relaxing muscle tone. It is a short-acting muscle relaxer that works by blocking nerve impulses (pain sensations) that are sent to your brain.

Tizanidine should be used on a short term basis. Long term use of this medication can have serious effects on the individuals health.

The misuse of Tizanidine can pose a danger to the individuals health. Potentially leading to a tolerance, dependency and withdrawal syndrome.

Tizanidine Dosage and Directions

The recommended dose for a patient with increased muscle tone associated with spasticity related to multiple sclerosis or spinal cord injury is 4 mg orally once a day. The dose of tizanidine may be repeated as needed at 6 to 8 hour intervals to a maximum dose 3 doses per 24 hours. Dose should not exceed 36 mg. The use of single doses greater than 12 mg is not recommended.