What is Mescaline?

Mescaline is a hallucinogen that comes from the spineless cactus Peyote (Lophophora williamsi). Mescaline has been used throughout time by natives in northern Mexico and the southwestern United States as a part of traditional religious rites. Those who use Mescaline are doing so for the rich visual hallucinations. It is most commonly used for recreational and spiritual purpose. Mescaline was also used in the 20th century as an supplement in many types of medication and in psychedelic therapy.

Mescaline is created by removing the top of the cactus from the roots, cutting them into buttons that are then dried. The buttons are then chewed or soaked in water to produce an intoxicating liquid that creates hallucinogenic effects that last about 12 hours. Mescaline can also be created synthetically within a laboratory.

The Effects of Mescaline


When ingested, Mescaline enters into the gastrointestinal track, then enters into the blood stream and makes it way to the brain. When in the brain it directly effects the neurotransmitters that control serotonin,  dopamine and norepinephrine.  Mescaline creates visual hallucinations, altered states of consciousness, euphoria, dream-like state, laughter and a psychedelic experience. Some Mescaline users will experience unwanted effects of feelings of anxiety or revulsion.

What is Mescaline Used For?

Mescaline was used in the 20th century as an supplement in many types of medications, as well as in psychedelic therapy. However, Mescaline was found to be of no use in these medical applications, making the drug useless medically. Over a dozen states had outlawed possession of Mescaline by 1930. Eventually mescaline was banned in the U.S. in 1967 and soon after placed on Schedule I in 1970.

Today Mescaline is still used in Native American Cultures within New Mexico and Texas for spiritual rites. However its cultivation, sale and use is still illegal throughout the United States.

This hallucinogenic drug is most commonly used illegally for recreational purposes throughout the US. People abuse Mescaline for its visual hallucinations, altered states of consciousness, euphoria, dream-like state, laughter and a psychedelic experience. It is used as a club drug at parties and raves for its effects and ability to keep the person awake for hours on end without sleep.

Signs and Symptoms of Mescaline Abuse

Mescaline is not a physically addictive drug, however it does hold psychologically addictive effects that make it a danger to its users. After its first use a person can become addicted to its psychedelic effects, using it on a regular basis. The more often it is used the more of the drug the person will need to acheive the desired effects, this can be a danger of producing health effects and damage to the brain.

Club drugs such as Mescaline are typically used in binges where the person takes the drug throughout the weekend, partying without sleep and then crashes when stopping its use. They may seem energetic throughout the weekend, excitable and more outgoing. On week days they will seem weak, fatigued, uncomfortable and irritable. By the time the weekend returns the use of Mescaline relieves their discomfort and another binge begins.

Mescaline Addiction Treatment

Mescaline addicts are not physically addicted to the drug but are psychologically addicted to its effects and the lifestyle that goes along with it, making it just as difficult to quit. Treatment for Mescaline addiction involves the patient packing up and entering into a residential treatment program where they are removed from temptation and the lifestyle that goes along with drug abuse. The patient will find a safe, secure and therapeutic environment to work through their psychological addiction to Mescaline with the help of trained chemical dependency specialists.

Cognitive Therapy is the most important form of psychotherapy treatment the patient will receive. It allows the patient to recognize the dysfunctional thoughts, behaviors and routines that go along with Mescaline abuse. Having the ability to identify them allows the patient to consciously make changes to healthy, sober living. Cognitive therapy will allow the patient to develop the tools they need to say no to temptation and make the lifestyle changes needed to remain sober.